| ACTIVE | PLAYER | TITLES |
|---|---|---|
| Bill Tilden | 7 | |
| William Larned | 7 | |
| Richard Sears | 7 | |
| Roger Federer | 5 | |
| Pete Sampras | 5 | |
| Jimmy Connors | 5 | |
| A | Rafael Nadal | 4 |
| A | Novak Djokovic | 4 |
| John McEnroe | 4 | |
| Robert Wrenn | 4 | |
| Ivan Lendl | 3 | |
| Oliver Campbell | 3 | |
| Fred Perry | 3 | |
| Malcolm Whitman | 3 | |
| Andre Agassi | 2 | |
| Don Budge | 2 | |
| Stefan Edberg | 2 | |
| Roy Emerson | 2 | |
| Neale Fraser | 2 | |
| Pancho Gonzales | 2 | |
| Bill Johnston | 2 | |
| Jack Kramer | 2 | |
| René Lacoste | 2 | |
| Rod Laver | 2 | |
| Maurice McLoughlin | 2 | |
| Robert Lindley Murray | 2 | |
| John Newcombe | 2 | |
| Frank Parker | 2 | |
| Patrick Rafter | 2 | |
| Bobby Riggs | 2 | |
| Ken Rosewall | 2 | |
| Frank Sedgman | 2 | |
| Henry Slocum | 2 | |
| Tony Trabert | 2 | |
| Ellsworth Vines | 2 | |
| Richard Norris Williams | 2 | |
| A | Carlos Alcaraz | 1 |
| A | Daniil Medvedev | 1 |
| Dominic Thiem | 1 | |
| A | Stanislas Wawrinka | 1 |
| A | Marin Čilić | 1 |
| A | Jannik Sinner | 1 |
| Andy Murray | 1 | |
| Juan Martín del Potro | 1 | |
| Andy Roddick | 1 | |
| Lleyton Hewitt | 1 | |
| Marat Safin | 1 | |
| Boris Becker | 1 | |
| Mats Wilander | 1 | |
| Guillermo Vilas | 1 | |
| Manuel Orantes | 1 | |
| Ilie Năstase | 1 | |
| Stan Smith | 1 | |
| Arthur Ashe | 1 | |
| Fred Stolle | 1 | |
| Manuel Santana | 1 | |
| Rafael Osuna | 1 | |
| Ashley Cooper | 1 | |
| Malcolm Anderson | 1 | |
| E. Victor Seixas | 1 | |
| Arthur Larsen | 1 | |
| Joseph Hunt | 1 | |
| Ted Schroeder | 1 | |
| Don McNeil | 1 | |
| Bobby Riggs | 1 | |
| Wilmer Allison | 1 | |
| John Doeg | 1 | |
| Henri Cochet | 1 | |
| William Clothier | 1 | |
| Beals Wright | 1 | |
| Holcombe Ward | 1 | |
| Laurence Doherty | 1 | |
| Frederick Hovey | 1 |
Table: List of Most US Open Titles Men, Tennis, Ranked.